SEMG2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q02383 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 65 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human SEMG2 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
SUBCELLULAR LOCATION | Secreted. |
SIMILARITY | Belongs to the semenogelin family. |
Post-translational modifications | Semenogelin-2 is thought to form both the 71 kDa polypeptide and, in its glycosylated form, the 76 kDa polypeptide. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015] |
Gene ID | 6407 |
---|---|
Other Names | Semenogelin-2, Semenogelin II, SGII, SEMG2 |
Target/Specificity | Seminal vesicles, and to a much lesser extent, epididymis. |
Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | SEMG2 |
---|---|
Function | Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa. |
Cellular Location | Secreted. |
Tissue Location | Seminal vesicles, and to a much lesser extent, epididymis |

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